Traditional Anomaly Detection (AD) methods have predominantly relied on unsupervised learning from extensive normal data.

Industrial image anomaly detection is a challenging problem owing to extreme class imbalance and the scarcity of labeled defective samples, particularly in few-shot settings. We propose BayPrAnoMeta, a Bayesian generalization of Proto-MAML for few-shot industrial image anomaly detection. Unlike existing Proto-MAML approaches that rely on deterministic class prototypes and distance-based adaptation, BayPrAnoMeta replaces prototypes with task-specific probabilistic normality models and performs inner-loop adaptation via a Bayesian posterior predictive likelihood. We model normal support embeddings with a Normal-Inverse-Wishart (NIW) prior, producing a Student-$t$ predictive distribution that enables uncertainty-aware, heavy-tailed anomaly scoring and is essential for robustness in extreme few-shot settings. We further extend BayPrAnoMeta to a federated meta-learning framework with supervised contrastive regularization for heterogeneous industrial clients and prove convergence to stationary points of the resulting nonconvex objective. Experiments on the MVTec AD benchmark demonstrate consistent and significant AUROC improvements over MAML, Proto-MAML, and PatchCore-based methods in few-shot anomaly detection settings.

Unknown anomaly detection in medical imaging remains a fundamental challenge due to the scarcity of labeled anomalies and the high cost of expert supervision. We introduce an unsupervised, oracle-free framework that incrementally expands a trusted set of normal samples without any anomaly labels. Starting from a small, verified seed of normal images, our method alternates between lightweight adapter updates and uncertainty-gated sample admission. A frozen pretrained vision backbone is augmented with tiny convolutional adapters, ensuring rapid domain adaptation with negligible computational overhead. Extracted embeddings are stored in a compact coreset enabling efficient k-nearest neighbor anomaly (k-NN) scoring. Safety during incremental expansion is enforced by dual probabilistic gates, a sample is admitted into the normal memory only if its distance to the existing coreset lies within a calibrated z-score threshold, and its SWAG-based epistemic uncertainty remains below a seed-calibrated bound. This mechanism prevents drift and false inclusions without relying on generative reconstruction or replay buffers. Empirically, our system steadily refines the notion of normality as unlabeled data arrive, producing substantial gains over baselines. On COVID-CXR, ROC-AUC improves from 0.9489 to 0.9982 (F1: 0.8048 to 0.9746); on Pneumonia CXR, ROC-AUC rises from 0.6834 to 0.8968; and on Brain MRI ND-5, ROC-AUC increases from 0.6041 to 0.7269 and PR-AUC from 0.7539 to 0.8211. These results highlight the effectiveness and efficiency of the proposed framework for real-world, label-scarce medical imaging applications.

Flexible microelectrode (FME) implantation into brain cortex is challenging due to the deformable fiber-like structure of FME probe and the interaction with critical bio-tissue. To ensure reliability and safety, the implantation process should be monitored carefully. This paper develops an image-based anomaly detection framework based on the microscopic cameras of the robotic FME implantation system. The unified framework is utilized at four checkpoints to check the micro-needle, FME probe, hooking result, and implantation point, respectively. Exploiting the existing object localization results, the aligned regions of interest (ROIs) are extracted from raw image and input to a pretrained vision transformer (ViT). Considering the task specifications, we propose a progressive granularity patch feature sampling method to address the sensitivity-tolerance trade-off issue at different locations. Moreover, we select a part of feature channels with higher signal-to-noise ratios from the raw general ViT features, to provide better descriptors for each specific scene. The effectiveness of the proposed methods is validated with the image datasets collected from our implantation system.